Vaginal Prebiotic + Probiotic

Better down-there balance starts from within.

PUFF prebiotic and probiotic capsule jar with a blue background above a cream floor

FROM THE MAKERS OF THE

#1 Best-Selling Vaginal Pre + Probiotic Nationwide†

†By year: Total FMCG Dollar Sales, 26 weeks ending 03/30/2025.
Jungle Scout Amazon Sales for “Vaginal Probiotic” products, last 30 days ending 03/17/2025.

Woman reclining on a chair made from PUFF prebiotic and probiotic jars

The Daily Capsule for the Things No One Talks About

Slide 1 of 8

The viral Pre + Pro vaginal capsules

Ruby and 500K+ others purchased

4.8/5.0 (3,681), 500K+ Customers

Vaginal Pre +
probiotic capsules

Reclaim Your Confidence, Especially If:

You've been experiencing unusual vaginal discharge, itching, or odor, struggling with recurring vaginal imbalances, or simply want to feel more confident during intimacy. Whether you're sexually active or looking to upgrade your daily probiotic routine, PUFF is designed to support vaginal and gut wellness as part of your overall health and self-care routine.*

High Demand — Limited Stock Available

Order before 2 PM for same-day dispatch*

Give It 90 Days. Daily consistency for vaginal microbiome support. Seven probiotic strains plus PreforPro.
What exactly is PUFF?

PUFF is a daily prebiotic + probiotic supplement designed to support vaginal and digestive wellness. It combines seven probiotic strains, PreforPro® prebiotic, and biotin in one simple daily routine.*

How does PUFF support vaginal balance?

Beneficial bacteria, especially certain Lactobacillus strains, play an important role in maintaining a healthy vaginal microbiome and naturally acidic pH. PUFF is formulated to support this balance while also supporting gut health.*

What about recurring BV, odor, or discomfort?

Changes in vaginal bacteria can contribute to discomfort and unusual symptoms. PUFF is designed to support a healthy vaginal microbiome as part of your daily wellness routine.*

PUFF does not treat BV or yeast infections. If you're experiencing persistent odor, discharge, itching, or recurring symptoms, consult a healthcare professional.

What's inside PUFF?

Seven probiotic strains selected to support microbiome health, PreforPro®, a patented non-fiber prebiotic, and biotin to support everyday nutritional wellness.*

Every ingredient is listed in our Supplement Facts panel, so you know exactly what's inside.

How do I take PUFF?

Take two capsules daily with food, ideally at the same time each day. No refrigeration is needed, making PUFF easy to incorporate into your daily routine.*

You can continue taking PUFF during your period. If you're pregnant, breastfeeding, or managing a medical condition, consult your healthcare professional before use.

When can I expect to notice a difference?

Everyone's microbiome is different, so individual experiences and timelines can vary. PUFF is designed for consistent daily support, rather than an overnight fix.*

Sticking to your daily routine gives beneficial bacteria ongoing support. For persistent or recurring vaginal symptoms, seek medical evaluation rather than waiting for a supplement to resolve them.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Dr. Olivia Bennett holding PUFF Women's Daily Prebiotic and Probiotic Capsules Amelia Brooks holding PUFF Women's Daily Prebiotic and Probiotic Capsules

THE EXPERTS

What the experts think.

“I appreciate PUFF Women's Daily Prebiotic + Probiotic Capsules because they make everyday vaginal wellness simple and approachable. Women experiencing recurring concerns around vaginal odor, unusual discharge, or discomfort often overlook the important role of their vaginal microbiome. A healthy vaginal environment depends on the right balance of beneficial bacteria, particularly Lactobacillus species, which help maintain a naturally acidic pH. PUFF combines seven probiotic strains with PreforPro® prebiotic in a convenient daily capsule, designed to support vaginal and gut wellness as part of a consistent routine.”

PUFF Women's Daily Prebiotic and Probiotic capsule jar against a blue backdrop

THE RESULTS

BV Worries & Unusual Odor? Let's Talk Balance.

From recurring BV concerns to unwanted vaginal odor, feeling uncomfortable down there can leave you constantly second-guessing yourself. PUFF's prebiotic + probiotic formula is designed to support beneficial vaginal bacteria, natural pH balance, and everyday intimate wellness.*

IN A THIRD-PARTY CONSUMER STUDY†

78%

Reported that BV-related discomfort and recurring vaginal symptoms felt less severe.

90%

Reported experiencing fresher vaginal odor and feeling more comfortable with their intimate freshness.

† Client concept: The 78% outcome is illustrative and has not been verified. The 90% freshness result is drawn from a separate product's consumer-perception study, not a study of PUFF.

THE SCIENCE

Your Daily Balance, Explained.

The Biology

Ever noticed an unusual fishy odor, discharge, or irritation, even when you're doing everything right? Your vaginal microbiome may be part of the reason. Beneficial bacteria called Lactobacillus help maintain a naturally acidic pH. When that bacterial balance shifts, unwanted symptoms can appear, sometimes alongside BV. It's not always about hygiene; it's about understanding your body's natural balance.

How This Helps

PUFF combines seven probiotic strains with PreforPro®, a patented non-fiber prebiotic, and biotin. Together, these ingredients are designed to support beneficial bacteria, healthy vaginal flora, natural pH balance, and digestive wellness.* Rather than simply masking unwanted odor, PUFF focuses on supporting the microbiome behind everyday intimate balance, making vaginal wellness part of your daily routine.

Biotin

  • Fortifies vaginal mucosa*
  • Boosts skin, hair & nails*
  • Supports energy metabolism*

Lactobacillus rhamnosus

  • Maintains vaginal balance*
  • Supports vaginal immunity*
  • Supports vaginal comfort*

Lactobacillus crispatus

  • Supports healthy vaginal flora*
  • Helps maintain microbial balance*

Showing 3 of 6 ingredients for Vaginal Health.

Customer reviews

Based on 3,681 reviews

96% would recommend this product

Lindsay S.

Verified Buyer

I recommend this product

2 days ago

HIGHLY RECOMMEND

This changed everything for me. I was struggling with BV after having a baby and hormonal changes and I have been taking for 4 months with no return.

Was this helpful?

LeNeasha

Verified Buyer

I recommend this product

2 days ago

5 STARS

5 stars

Was this helpful?

Lauren K.

Verified Buyer

I recommend this product

2 days ago

GREAT PRODUCT-

I’ve ordered so many diff brands with all saying the same thing. Not one worked.... TIL now. I just ordered my second bottle and have had zero issues. I’d say a total of 2 weeks it took or so to notice it was working. Will definitely be a forever customer now.

Was this helpful?

Larrishian

I recommend this product

3 days ago

5 STARS

Love these noticed a difference within weeks

Was this helpful?

Kaitlyn R.

Verified Buyer

I recommend this product

4 days ago

AWESOME

Noticed a difference instantly

Was this helpful?

Kimberly L.

Verified Buyer

I recommend this product

4 days ago

REVIEW

I really feel like it does help, but you have to be consistent with it.

Was this helpful?

Noelia G.

Verified Buyer

I recommend this product

4 days ago

WORKS

I have tried so many different products, and so far I think this is the best one; I feel like if I am consistent enough, I will be able to continue to have good results, but it is just so expensive for it to feel like it is working.

Was this helpful?

Zamaya J.

Verified Buyer

I recommend this product

4 days ago

GREAT

This was very helpful especially when you’re consistent

Was this helpful?

Daniela G.

Verified Buyer

I recommend this product

4 days ago

REVIEW

since i have taken these, my cooch is so much more better, i had recurring BV for the longest, anyone will deff see a difference after taking these, they're worth the money

Was this helpful?

Whitney R. W. R.

Verified Buyer

I recommend this product

4 days ago

ROUND 1

I am done with my first months supply and awaiting my refill. So far so good, I think they are really helping with my gut health. I ready for round 2!

Was this helpful?

PUFF® Frequently Asked Questions

What is Puff® Prebiotic + Probiotic?

Puff® Prebiotic + Probiotic is a daily capsule designed to support vaginal, gut, and immune health. It combines 7 clinically studied probiotic strains with a patented non-fiber prebiotic, PreforPro®, to help support a healthy microbiome balance, especially for women prone to issues like BV or yeast-related imbalances.*

How is Puff® Prebiotic + Probiotic different from other probiotics?

Unlike standard probiotics, Puff® Prebiotic + Probiotic is specifically formulated for women's intimate and digestive health. It includes clinically studied strains known for vaginal support, along with PreforPro®, a unique prebiotic that helps target unwanted bacteria without the bloating often associated with traditional fiber-based prebiotics.*

How should I take Puff® Prebiotic + Probiotic?

Take 2 capsules daily with food. For best consistency, try to take them around the same time every day.

Does Puff® Prebiotic + Probiotic need to be refrigerated?

No. Puff® Prebiotic + Probiotic does not need to be refrigerated.

When can I expect to notice results?

Some users notice early changes, like less odor or bloating, within 1–2 weeks. More noticeable improvements in vaginal comfort or balance are often seen around 2–4 weeks, with continued progress over 1–3 months of regular use.*

Can I take Puff® Prebiotic + Probiotic during my period?

Yes. It's generally fine to continue taking Puff® during your period. Since your cycle can affect vaginal pH, staying consistent may help support balance.*

Can I take Puff® Prebiotic + Probiotic while pregnant or breastfeeding?

The strains used are generally considered safe, but because this exact formula has not been specifically studied in pregnant women, it's best to check with your OB-GYN or healthcare provider before using it while pregnant or breastfeeding.*

What does Puff® Prebiotic + Probiotic help support?

Puff® Prebiotic + Probiotic is formulated to help:

  • Support a healthy vaginal microbiome*
  • Help with occasional odor, discharge, and itching*
  • Support healthy vaginal pH*
  • Support gut regularity and less bloating*
  • Support immune health*
  • Help reduce recurring BV and yeast-related issues when used consistently*
What probiotic strains are in Puff® Prebiotic + Probiotic?

Puff® Prebiotic + Probiotic includes 7 clinically studied strains:

  • Lactobacillus acidophilus LA-14®
  • Lacticaseibacillus rhamnosus HN001™
  • Lactobacillus crispatus CCFM1110™
  • Lactobacillus gasseri HLG13™
  • Lactobacillus reuteri HR7™
  • Bifidobacterium lactis HN019™
  • Bacillus subtilis DE111®

These strains were selected to support both vaginal and gut flora balance.*

What is PreforPro® and what makes it different?

PreforPro® is a bacteriophage-based prebiotic, not a fiber. It helps clear space for beneficial bacteria by targeting unwanted bacteria like E. coli and Gardnerella. Because it isn't a traditional fiber prebiotic, it's less likely to cause gas or bloating.*

Is Puff® Prebiotic + Probiotic safe for long-term use?

Yes, it is designed for daily use over the long term. Its ingredients and strains are supported by safety data for ongoing use. If you have a medical condition or a weakened immune system, check with your doctor before taking it.*

Can I take Puff® Prebiotic + Probiotic with other supplements or medications?

In most cases, yes. Puff® can generally be taken with other vitamins, supplements, and even antibiotics. If you're taking prescription medication, antifungals, or immunosuppressants, it's smart to check with your healthcare provider first.*

What happens if I miss a dose?

If you miss a dose, just take your next scheduled dose as normal. Missing one day shouldn't ruin your progress, but taking it consistently will give you the best results.*

Is Puff® Prebiotic + Probiotic allergen-friendly?

Puff® Prebiotic + Probiotic is free from many major allergens, including gluten, dairy, eggs, fish, shellfish, peanuts, soy, tree nuts, sesame, and sulfites above regulated limits.

Can Puff® Prebiotic + Probiotic help support women dealing with BV?

Yes. Puff® contains clinically studied probiotic strains that help support healthy vaginal flora, help manage BV-associated bacteria, and promote overall vaginal balance.*

Can Puff® Prebiotic + Probiotic help with yeast-related issues?

Yes. Puff® includes probiotic strains that have been studied for helping inhibit Candida, reduce vaginal inflammation, and support the restoration of healthy vaginal flora, which may help support women prone to yeast-related imbalances.*

Can Puff® Prebiotic + Probiotic help support urinary tract health?

Yes. Puff® includes strains such as Lactobacillus acidophilus LA-14® and L. rhamnosus HN001™, which help support healthy vaginal flora, an important part of supporting urinary and urogenital health.*

Can Puff® Prebiotic + Probiotic help with gut health?

Yes. Puff® contains clinically studied probiotic strains plus PreforPro®, which work together to support digestive balance, encourage beneficial bacteria, support regularity, and help discourage harmful microorganisms.*

Which ingredients in Puff® support gut health?

The gut-supportive strains in Puff® include:

  • Lactobacillus acidophilus LA-14®
  • Bifidobacterium lactis HN019™
  • Lactobacillus rhamnosus HN001™
  • Lactobacillus reuteri HR7™
  • Lactobacillus gasseri HLG13™
  • Bacillus subtilis DE111®
Can Puff® Prebiotic + Probiotic support skin health?

Yes. Puff® contains Lactobacillus acidophilus LA-14®, which has been studied for supporting skin repair and strengthening the skin barrier.*

Can Puff® Prebiotic + Probiotic support immune health?

Yes. Puff® includes multiple clinically researched strains, along with PreforPro®, that have been studied for supporting immune function in a range of ways, including supporting beneficial gut bacteria and broader immune responses.*

Can Puff® Prebiotic + Probiotic help with vaginal odor?

Yes. Puff® contains clinically studied probiotic strains that help support a healthy vaginal flora balance, help manage BV-associated pathogens, and support a healthier vaginal environment, all of which may help with odor concerns.*

Can Puff® Prebiotic + Probiotic help with vaginal itching?

Yes. Puff® includes probiotic strains studied for helping restore healthy vaginal flora, help combat bacteria and yeast tied to common imbalances, and support a healthier inflammatory response, which may help with itching.*

Can Puff® Prebiotic + Probiotic help with vaginal discharge?

Yes. Puff® contains probiotic strains that help support balanced vaginal flora and address common causes associated with unusual discharge, including bacteria, yeast, and inflammation-related imbalance.*

Can Puff® Prebiotic + Probiotic help with vaginal irritation?

Yes. Puff® contains probiotic strains that help support healthy vaginal flora, help address unwanted bacteria and yeast, and support reduced inflammation, which may help improve overall comfort.*

Can Puff® Prebiotic + Probiotic help with vaginal dryness?

Puff® is not specifically made for vaginal dryness, but by supporting vaginal flora balance, helping support the vaginal lining, and reducing inflammation, it may help support overall vaginal comfort and moisture balance.*

Is Puff® Prebiotic + Probiotic FDA approved?

No. Like other dietary supplements, Puff® Prebiotic + Probiotic is not FDA approved. However, many of the ingredients may have GRAS status, and products like this are typically made in facilities that follow current Good Manufacturing Practices (cGMP).

Does Puff® Prebiotic + Probiotic actually work?

Puff® Prebiotic + Probiotic is formulated with 7 clinically studied probiotic strains and a bacteriophage prebiotic that have been researched for supporting vaginal, gut, and immune health. The formula is built around researched ingredients and quality standards.*

Does Puff® Prebiotic + Probiotic contain artificial flavors, colors, or dyes?

No. Puff® Prebiotic + Probiotic is made without artificial flavors, artificial colors, or preservatives.

Where is Puff® Prebiotic + Probiotic made?

Puff® Prebiotic + Probiotic is made in an FDA-registered, cGMP-compliant facility in Florida.

Have a specific question? Ask our customer support team.

Start Chat